Product

MOTS-C 

Details:​

A 16-amino-acid mitochondrial-derived peptide (MDP) encoded within the 12S ribosomal RNA region of the mitochondrial genome. It functions as a systemic mitochondrial hormone that translocates to the nucleus under metabolic stress to regulate nuclear gene expression, directly activating the AMPK (adenosine monophosphate-activated protein kinase) pathway and re-sensitizing tissues to glucose and fatty acid uptake.

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Key Benefits:

• AMPK Activation & Metabolic Regulation: Stimulates the central energy-sensing AMPK enzyme complex, mimicking the metabolic benefits of high-intensity endurance exercise.

• Enhanced Glucose Uptake & Insulin Sensitivity: Enhances GLUT4 translocation to muscle cells, clearing circulating glucose independently of insulin and reducing insulin resistance.

• Optimized Lipid Oxidation: Upregulates fatty acid breakdown while suppressing diet-induced fat accumulation and hepatic steatosis (fatty liver).

• Mitochondrial Biogenesis & Stamina: Enhances cellular respiration, ATP generation efficiency, and systemic endurance under physical stress.

• Protection Against Age-Related Decline: Counteracts muscle wasting (sarcopenia) and systemic metabolic slowdown associated with natural biological aging.

Ideal For:

• Athletic performance and endurance optimization, particularly for sustained aerobic output, metabolic efficiency, and accelerated physical recovery.

• Individuals targeting metabolic syndrome, insulin resistance, pre-diabetic states, or stubbornly slow metabolic rates.

• Longevity and anti-aging regimens focused on preserving mitochondrial health, lean tissue retention, and cellular energy dynamics.