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Selank

Details:​

A synthetic heptapeptide derived from the endogenous immunomodulatory tetrapeptide Tuftsin (Thr-Lys-Pro-Arg), elongated with a Pro-Gly-Pro sequence at the C-terminus to enhance metabolic stability and prolong enzymatic resistance. Developed by the Institute of Molecular Genetics of the Russian Academy of Sciences, it acts as an anxiolytic and nootropic regulatory peptide that modulates GABAergic transmission, stabilizes central serotonin and dopamine metabolism, and regulates systemic enkephalin breakdown, delivering profound anti-anxiety and stress-modulating effects without sedation or addiction potential.

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Key Benefits:

  • Non-Sedative Anxiolysis: Exerts pronounced stress-reducing and anti-anxiety effects comparable to classic benzodiazepines, but without motor impairment, mental fog, sedation, or withdrawal liabilities.

  • GABA & Neurotransmitter Balancing: Modulates GABA-A receptor affinity while stabilizing central serotonergic and dopaminergic activity, smoothing out emotional volatility and generalized tension.

  • BDNF & Nootropic Support: Increases Brain-Derived Neurotrophic Factor (BDNF) expression in the hippocampus, supporting learning capacity, sensory processing, and memory consolidation under acute stress.

  • Enkephalinase Inhibition: Slows the enzymatic degradation of endogenous enkephalins (natural endorphins), prolonging natural pain-dampening, mood elevation, and stress-buffering mechanisms.

  • Immunomodulatory Action: Inherits Tuftsin’s native properties to regulate interleukin-6 (IL-6) and other pro-inflammatory cytokines, balancing immune response during chronic systemic stress.

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Ideal For:

  • High-stress lifestyle management, generalized anxiety, or performance anxiety where sharp, unimpaired mental clarity is essential.

  • Nootropic stacks and mental optimization, especially when combined with Semax to balance calm focus with executive drive.

  • Individuals discontinuing GABAergic agents or seeking non-habit-forming support for chronic nervous system hyperarousal, burnout, and emotional fatigue.

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